2deb: Difference between revisions
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New page: left|200px<br /><applet load="2deb" size="450" color="white" frame="true" align="right" spinBox="true" caption="2deb, resolution 1.60Å" /> '''Crystal structure of... |
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[[Image:2deb.jpg|left|200px]]<br /><applet load="2deb" size=" | [[Image:2deb.jpg|left|200px]]<br /><applet load="2deb" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="2deb, resolution 1.60Å" /> | caption="2deb, resolution 1.60Å" /> | ||
'''Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221'''<br /> | '''Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221'''<br /> | ||
==Overview== | ==Overview== | ||
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system | Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association. | ||
==About this Structure== | ==About this Structure== | ||
2DEB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with BOG, COA and PLM as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21] Full crystallographic information is available from [http:// | 2DEB is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=BOG:'>BOG</scene>, <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=PLM:'>PLM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEB OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Banner, D | [[Category: Banner, D W.]] | ||
[[Category: Benz, J.]] | [[Category: Benz, J.]] | ||
[[Category: Chomienne, O.]] | [[Category: Chomienne, O.]] | ||
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[[Category: Hennig, M.]] | [[Category: Hennig, M.]] | ||
[[Category: Mueller, F.]] | [[Category: Mueller, F.]] | ||
[[Category: Roo, E | [[Category: Roo, E De.]] | ||
[[Category: Rufer, A | [[Category: Rufer, A C.]] | ||
[[Category: Stihle, M.]] | [[Category: Stihle, M.]] | ||
[[Category: Thoma, R.]] | [[Category: Thoma, R.]] | ||
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[[Category: central six-stranded beta-sheet]] | [[Category: central six-stranded beta-sheet]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:57:58 2008'' | ||
Revision as of 14:57, 21 February 2008
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Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221
Overview
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
About this Structure
2DEB is a Single protein structure of sequence from Rattus norvegicus with BOG, COA and PLM as ligands. Active as Carnitine O-palmitoyltransferase, with EC number 2.3.1.21 Full crystallographic information is available from OCA.
Reference
A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901
Page seeded by OCA on Thu Feb 21 16:57:58 2008
