3ckp: Difference between revisions
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[[Image:3ckp.png|left|200px]] | [[Image:3ckp.png|left|200px]] | ||
{{STRUCTURE_3ckp| PDB=3ckp | SCENE= }} | {{STRUCTURE_3ckp| PDB=3ckp | SCENE= }} | ||
===Crystal structure of BACE-1 in complex with inhibitor=== | ===Crystal structure of BACE-1 in complex with inhibitor=== | ||
{{ABSTRACT_PUBMED_18434152}} | {{ABSTRACT_PUBMED_18434152}} | ||
==About this Structure== | ==About this Structure== | ||
[[3ckp]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKP OCA]. | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018434152</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Min, K.]] | [[Category: Min, K.]] | ||
[[Category: Aspartyl protease]] | [[Category: Aspartyl protease]] | ||
[[Category: Beta-secretase]] | [[Category: Beta-secretase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 18:34, 26 July 2012
Crystal structure of BACE-1 in complex with inhibitor
Template:ABSTRACT PUBMED 18434152
About this Structure
3ckp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Park H, Min K, Kwak HS, Koo KD, Lim D, Seo SW, Choi JU, Platt B, Choi DY. Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives. Bioorg Med Chem Lett. 2008 May 1;18(9):2900-4. Epub 2008 Apr 8. PMID:18434152 doi:10.1016/j.bmcl.2008.03.081