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{{Seed}}
[[Image:2vem.png|left|200px]]
[[Image:2vem.png|left|200px]]


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{{STRUCTURE_2vem|  PDB=2vem  |  SCENE=  }}  
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===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES===
===STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES===


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{{ABSTRACT_PUBMED_18239072}}
{{ABSTRACT_PUBMED_18239072}}


==About this Structure==
==About this Structure==
2VEM is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEM OCA].  
[[2vem]] is a 2 chain structure of [[TIM test]] and [[Triose Phosphate Isomerase]] with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VEM OCA].  
 
==See Also==
*[[TIM test|TIM test]]
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18239072</ref><references group="xtra"/>
<ref group="xtra">PMID:018239072</ref><references group="xtra"/>
[[Category: Triose-phosphate isomerase]]
[[Category: Triose-phosphate isomerase]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Trypanosoma brucei brucei]]
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[[Category: Tim barrel]]
[[Category: Tim barrel]]
[[Category: Triosephosphate isomerase]]
[[Category: Triosephosphate isomerase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:55:50 2009''

Revision as of 19:04, 26 July 2012

File:2vem.png

Template:STRUCTURE 2vem

STRUCTURE-BASED ENZYME ENGINEERING EFFORTS WITH AN INACTIVE MONOMERIC TIM VARIANT: THE IMPORTANCE OF A SINGLE POINT MUTATION FOR GENERATING AN ACTIVE SITE WITH SUITABLE BINDING PROPERTIES

Template:ABSTRACT PUBMED 18239072

About this Structure

2vem is a 2 chain structure of TIM test and Triose Phosphate Isomerase with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

See Also

Reference

  1. Alahuhta M, Salin M, Casteleijn MG, Kemmer C, El-Sayed I, Augustyns K, Neubauer P, Wierenga RK. Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties. Protein Eng Des Sel. 2008 Apr;21(4):257-66. Epub 2008 Jan 31. PMID:18239072 doi:https://dx.doi.org/10.1093/protein/gzn002

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