1wok: Difference between revisions

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{{Seed}}
[[Image:1wok.png|left|200px]]
[[Image:1wok.png|left|200px]]


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{{STRUCTURE_1wok|  PDB=1wok  |  SCENE=  }}  
{{STRUCTURE_1wok|  PDB=1wok  |  SCENE=  }}  


===Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor===
===Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor===


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{{ABSTRACT_PUBMED_15733846}}
{{ABSTRACT_PUBMED_15733846}}
==Disease==
Known disease associated with this structure: Xeroderma pigmentosum (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=173870 173870]]


==About this Structure==
==About this Structure==
1WOK is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WOK OCA].  
[[1wok]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WOK OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15733846</ref><references group="xtra"/>
<ref group="xtra">PMID:015733846</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hattori, K.]]
[[Category: Hattori, K.]]
Line 42: Line 27:
[[Category: Yamamoto, H.]]
[[Category: Yamamoto, H.]]
[[Category: Protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:13:58 2009''

Revision as of 13:19, 5 January 2013

File:1wok.png

Template:STRUCTURE 1wok

Crystal structure of catalytic domain of human poly(ADP-ribose) polymerase complexed with a quinoxaline-type inhibitor

Template:ABSTRACT PUBMED 15733846

About this Structure

1wok is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Iwashita A, Hattori K, Yamamoto H, Ishida J, Kido Y, Kamijo K, Murano K, Miyake H, Kinoshita T, Warizaya M, Ohkubo M, Matsuoka N, Mutoh S. Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP-ribose) polymerase-1/2 inhibitors. FEBS Lett. 2005 Feb 28;579(6):1389-93. PMID:15733846 doi:10.1016/j.febslet.2005.01.036

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