7pck: Difference between revisions

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{{Seed}}
[[Image:7pck.png|left|200px]]
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{{STRUCTURE_7pck|  PDB=7pck  |  SCENE=  }}  
{{STRUCTURE_7pck|  PDB=7pck  |  SCENE=  }}  
===CRYSTAL STRUCTURE OF WILD TYPE HUMAN PROCATHEPSIN K===
===CRYSTAL STRUCTURE OF WILD TYPE HUMAN PROCATHEPSIN K===
{{ABSTRACT_PUBMED_10048321}}


==Disease==
[[http://www.uniprot.org/uniprot/CATK_HUMAN CATK_HUMAN]] Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:[http://omim.org/entry/265800 265800]]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.<ref>PMID:8703060</ref><ref>PMID:9529353</ref><ref>PMID:10491211</ref><ref>PMID:10878663</ref>


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==Function==
The line below this paragraph, {{ABSTRACT_PUBMED_10048321}}, adds the Publication Abstract to the page
[[http://www.uniprot.org/uniprot/CATK_HUMAN CATK_HUMAN]] Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.  
(as it appears on PubMed at http://www.pubmed.gov), where 10048321 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10048321}}


==About this Structure==
==About this Structure==
7PCK is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PCK OCA].  
[[7pck]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7PCK OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:10048321</ref><references group="xtra"/>
<ref group="xtra">PMID:010048321</ref><references group="xtra"/><references/>
[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Sivaraman, J.]]
[[Category: Sivaraman, J.]]
[[Category: Cysteine protease]]
[[Category: Cysteine protease]]
[[Category: Hydrolase]]
[[Category: Procathepsin k]]
[[Category: Procathepsin k]]
[[Category: Proregion]]
[[Category: Proregion]]
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Retrieved from "https://proteopedia.org/7pck"