1t2f: Difference between revisions

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{{Seed}}
[[Image:1t2f.png|left|200px]]
[[Image:1t2f.png|left|200px]]


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{{STRUCTURE_1t2f|  PDB=1t2f  |  SCENE=  }}  
{{STRUCTURE_1t2f|  PDB=1t2f  |  SCENE=  }}  


===Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid===
===Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid===


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{{ABSTRACT_PUBMED_15117937}}
{{ABSTRACT_PUBMED_15117937}}


==Disease==
==About this Structure==
Known disease associated with this structure: Lactate dehydrogenase-B deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=150100 150100]]
[[1t2f]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2F OCA].


==About this Structure==
==See Also==
1T2F is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2F OCA].
*[[Lactate Dehydrogenase|Lactate Dehydrogenase]]


==Reference==
==Reference==
<ref group="xtra">PMID:15117937</ref><references group="xtra"/>
<ref group="xtra">PMID:015117937</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: L-lactate dehydrogenase]]
[[Category: L-lactate dehydrogenase]]
Line 51: Line 39:
[[Category: Vivas, L.]]
[[Category: Vivas, L.]]
[[Category: Winter, V J.]]
[[Category: Winter, V J.]]
[[Category: Oxidoreductase]]
[[Category: Protein-ligand complex]]
[[Category: Protein-ligand complex]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:40:33 2009''

Revision as of 23:09, 26 July 2012

File:1t2f.png

Template:STRUCTURE 1t2f

Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid

Template:ABSTRACT PUBMED 15117937

About this Structure

1t2f is a 4 chain structure of Lactate Dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Cameron A, Read J, Tranter R, Winter VJ, Sessions RB, Brady RL, Vivas L, Easton A, Kendrick H, Croft SL, Barros D, Lavandera JL, Martin JJ, Risco F, Garcia-Ochoa S, Gamo FJ, Sanz L, Leon L, Ruiz JR, Gabarro R, Mallo A, Gomez de las Heras F. Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. J Biol Chem. 2004 Jul 23;279(30):31429-39. Epub 2004 Apr 26. PMID:15117937 doi:10.1074/jbc.M402433200

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