2vqq: Difference between revisions

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{{Seed}}
[[Image:2vqq.png|left|200px]]
[[Image:2vqq.png|left|200px]]


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{{STRUCTURE_2vqq|  PDB=2vqq  |  SCENE=  }}  
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===STRUCTURE OF HDAC4 CATALYTIC DOMAIN (A DOUBLE CYSTEINE-TO-ALANINE MUTANT) BOUND TO A TRIFLUOROMETHYLKETONE INHBITOR===
===STRUCTURE OF HDAC4 CATALYTIC DOMAIN (A DOUBLE CYSTEINE-TO-ALANINE MUTANT) BOUND TO A TRIFLUOROMETHYLKETONE INHBITOR===


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{{ABSTRACT_PUBMED_18614528}}


==About this Structure==
==About this Structure==
2VQQ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQQ OCA].  
[[2vqq]] is a 2 chain structure of [[Histone deacetylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VQQ OCA].  
 
==See Also==
*[[Histone deacetylase|Histone deacetylase]]


==Reference==
==Reference==
<ref group="xtra">PMID:18614528</ref><references group="xtra"/>
<ref group="xtra">PMID:018614528</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bottomley, M J.]]
[[Category: Bottomley, M J.]]
Line 39: Line 30:
[[Category: Chromatin]]
[[Category: Chromatin]]
[[Category: Chromatin regulator]]
[[Category: Chromatin regulator]]
[[Category: Coiled coil]]
[[Category: Cytoplasm]]
[[Category: Hdac]]
[[Category: Hdac]]
[[Category: Hdaci]]
[[Category: Hdaci]]
Line 48: Line 37:
[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Repressor]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
[[Category: Ubl conjugation]]
[[Category: Zinc]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:58:01 2009''

Revision as of 01:02, 27 July 2012

File:2vqq.png

Template:STRUCTURE 2vqq

STRUCTURE OF HDAC4 CATALYTIC DOMAIN (A DOUBLE CYSTEINE-TO-ALANINE MUTANT) BOUND TO A TRIFLUOROMETHYLKETONE INHBITOR

Template:ABSTRACT PUBMED 18614528

About this Structure

2vqq is a 2 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bottomley MJ, Lo Surdo P, Di Giovine P, Cirillo A, Scarpelli R, Ferrigno F, Jones P, Neddermann P, De Francesco R, Steinkuhler C, Gallinari P, Carfi A. Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain. J Biol Chem. 2008 Sep 26;283(39):26694-704. Epub 2008 Jul 8. PMID:18614528 doi:https://dx.doi.org/10.1074/jbc.M803514200

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