1sgi: Difference between revisions

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{{Seed}}
[[Image:1sgi.png|left|200px]]
[[Image:1sgi.png|left|200px]]


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{{STRUCTURE_1sgi|  PDB=1sgi  |  SCENE=  }}  
{{STRUCTURE_1sgi|  PDB=1sgi  |  SCENE=  }}  


===Crystal structure of the anticoagulant slow form of thrombin===
===Crystal structure of the anticoagulant slow form of thrombin===


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{{ABSTRACT_PUBMED_15152000}}
{{ABSTRACT_PUBMED_15152000}}


==Disease==
==About this Structure==
Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
[[1sgi]] is a 4 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SGI OCA].


==About this Structure==
==See Also==
1SGI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SGI OCA].
*[[Thrombin|Thrombin]]


==Reference==
==Reference==
<ref group="xtra">PMID:15152000</ref><references group="xtra"/>
<ref group="xtra">PMID:015152000</ref><ref group="xtra">PMID:016673263</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Prasad, S.]]
[[Category: Prasad, S.]]
[[Category: Allostery]]
[[Category: Allostery]]
[[Category: Hydrolase]]
[[Category: Thrombin]]
[[Category: Thrombin]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:54:26 2009''

Revision as of 02:22, 27 July 2012

File:1sgi.png

Template:STRUCTURE 1sgi

Crystal structure of the anticoagulant slow form of thrombin

Template:ABSTRACT PUBMED 15152000

About this Structure

1sgi is a 4 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200
  2. Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551

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