1u0n: Difference between revisions

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{{Seed}}
[[Image:1u0n.png|left|200px]]
[[Image:1u0n.png|left|200px]]


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{{STRUCTURE_1u0n|  PDB=1u0n  |  SCENE=  }}  
{{STRUCTURE_1u0n|  PDB=1u0n  |  SCENE=  }}  


===The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex===
===The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex===


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{{ABSTRACT_PUBMED_15665869}}
{{ABSTRACT_PUBMED_15665869}}
==Disease==
Known disease associated with this structure: Bernard-Soulier syndrome, benign autosomal dominant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Bernard-Soulier syndrome, type A OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], von Willebrand disease, platelet-type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]], Nonarteritic anterior ischemic optic neuropathy, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606672 606672]]


==About this Structure==
==About this Structure==
1U0N is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Bothrops_jararaca Bothrops jararaca] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0N OCA].  
[[1u0n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararaca Bothrops jararaca] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U0N OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15665869</ref><references group="xtra"/>
<ref group="xtra">PMID:015665869</ref><references group="xtra"/>
[[Category: Bothrops jararaca]]
[[Category: Bothrops jararaca]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Fukuda, K.]]
[[Category: Fukuda, K.]]
[[Category: Liddington, R C.]]
[[Category: Liddington, R C.]]
[[Category: Blood clotting]]
[[Category: C-type lectin fold]]
[[Category: C-type lectin fold]]
[[Category: Lrr motif]]
[[Category: Lrr motif]]
[[Category: Protein-protein complex]]
[[Category: Protein-protein complex]]
[[Category: Rossmann fold]]
[[Category: Rossmann fold]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:17:14 2009''

Revision as of 11:18, 5 January 2013

File:1u0n.png

Template:STRUCTURE 1u0n

The ternary von Willebrand Factor A1-glycoprotein Ibalpha-botrocetin complex

Template:ABSTRACT PUBMED 15665869

About this Structure

1u0n is a 4 chain structure with sequence from Bothrops jararaca and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Fukuda K, Doggett T, Laurenzi IJ, Liddington RC, Diacovo TG. The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation. Nat Struct Mol Biol. 2005 Feb;12(2):152-9. Epub 2005 Jan 16. PMID:15665869 doi:10.1038/nsmb892

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