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| [[Image:2fse.png|left|200px]] | | [[Image:2fse.png|left|200px]] |
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| ===Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen=== | | ===Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen=== |
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| {{ABSTRACT_PUBMED_16951351}} | | {{ABSTRACT_PUBMED_16951351}} |
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| ==Disease== | | ==About this Structure== |
| Known disease associated with this structure: Achondrogenesis-hypochondrogenesis, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Epiphyseal dysplasia, multiple, with myopia and deafness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Kniest dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Osteoarthrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SED congenita OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SED, Namaqualand type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SMED Strudwick type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Spondyloperipheral dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Stickler syndrome, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Vitreoretinopathy with phalangeal epiphyseal dysplasia ( OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]]
| | [[2fse]] is a 6 chain structure of [[Collagen]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSE OCA]. |
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| ==About this Structure== | | ==See Also== |
| 2FSE is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSE OCA].
| | *[[Collagen|Collagen]] |
| | *[[Major histocompatibility complex|Major histocompatibility complex]] |
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| ==Reference== | | ==Reference== |
| <ref group="xtra">PMID:16951351</ref><references group="xtra"/> | | <ref group="xtra">PMID:016951351</ref><references group="xtra"/> |
| [[Category: Homo sapiens]] | | [[Category: Homo sapiens]] |
| [[Category: Mus musculus]] | | [[Category: Mus musculus]] |
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| [[Category: Antigen presentation]] | | [[Category: Antigen presentation]] |
| [[Category: Collagen type ii]] | | [[Category: Collagen type ii]] |
| [[Category: Crystal structure]]
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| [[Category: Hla-dr1]] | | [[Category: Hla-dr1]] |
| | [[Category: Immune system]] |
| [[Category: Rheumatoid arthritis]] | | [[Category: Rheumatoid arthritis]] |
| | | [[Category: Structural protein]] |
| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:01:59 2009''
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