2i1m: Difference between revisions

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{{Seed}}
[[Image:2i1m.png|left|200px]]
[[Image:2i1m.png|left|200px]]


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{{STRUCTURE_2i1m|  PDB=2i1m  |  SCENE=  }}  
{{STRUCTURE_2i1m|  PDB=2i1m  |  SCENE=  }}  


===cFMS tyrosine kinase (tie2 KID) in complex with an arylamide inhibitor===
===cFMS tyrosine kinase (tie2 KID) in complex with an arylamide inhibitor===


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{{ABSTRACT_PUBMED_17132624}}
{{ABSTRACT_PUBMED_17132624}}


==Disease==
==About this Structure==
Known disease associated with this structure: Myeloid malignancy, predisposition to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164770 164770]]
[[2i1m]] is a 1 chain structure of [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1M OCA].


==About this Structure==
==See Also==
2I1M is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I1M OCA].
*[[Tyrosine kinase|Tyrosine kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17132624</ref><references group="xtra"/>
<ref group="xtra">PMID:017132624</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Kinase domain]]
[[Category: Kinase domain]]
[[Category: Kinase inhibitor complex]]
[[Category: Kinase inhibitor complex]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:57:30 2009''

Revision as of 05:55, 27 July 2012

File:2i1m.png

Template:STRUCTURE 2i1m

cFMS tyrosine kinase (tie2 KID) in complex with an arylamide inhibitor

Template:ABSTRACT PUBMED 17132624

About this Structure

2i1m is a 1 chain structure of Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Schubert C, Schalk-Hihi C, Struble GT, Ma HC, Petrounia IP, Brandt B, Deckman IC, Patch RJ, Player MR, Spurlino JC, Springer BA. Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors. J Biol Chem. 2007 Feb 9;282(6):4094-101. Epub 2006 Nov 28. PMID:17132624 doi:https://dx.doi.org/10.1074/jbc.M608183200

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