1n5o: Difference between revisions

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{{Seed}}
[[Image:1n5o.png|left|200px]]
[[Image:1n5o.png|left|200px]]


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{{STRUCTURE_1n5o|  PDB=1n5o  |  SCENE=  }}  
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===Structural consequences of a cancer-causing BRCA1-BRCT missense mutation===
===Structural consequences of a cancer-causing BRCA1-BRCT missense mutation===


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{{ABSTRACT_PUBMED_12427738}}
==Disease==
Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]]


==About this Structure==
==About this Structure==
1N5O is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5O OCA].  
[[1n5o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5O OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:12427738</ref><references group="xtra"/>
<ref group="xtra">PMID:012427738</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Glover, J N.M.]]
[[Category: Glover, J N.M.]]
[[Category: Williams, R S.]]
[[Category: Williams, R S.]]
[[Category: Antitumor protein]]
[[Category: Brca1]]
[[Category: Brca1]]
[[Category: Brct]]
[[Category: Brct]]
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[[Category: Missense mutation]]
[[Category: Missense mutation]]
[[Category: Protein folding]]
[[Category: Protein folding]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:06:44 2009''

Revision as of 20:11, 5 December 2012

File:1n5o.png

Template:STRUCTURE 1n5o

Structural consequences of a cancer-causing BRCA1-BRCT missense mutation

Template:ABSTRACT PUBMED 12427738

About this Structure

1n5o is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Williams RS, Glover JN. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation. J Biol Chem. 2003 Jan 24;278(4):2630-5. Epub 2002 Nov 8. PMID:12427738 doi:10.1074/jbc.M210019200

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