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{{Seed}}
[[Image:1zsn.png|left|200px]]
[[Image:1zsn.png|left|200px]]


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{{STRUCTURE_1zsn|  PDB=1zsn  |  SCENE=  }}  
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===Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives===
===Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives===


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{{ABSTRACT_PUBMED_16198563}}
{{ABSTRACT_PUBMED_16198563}}


==About this Structure==
==About this Structure==
1ZSN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZSN OCA].  
[[1zsn]] is a 2 chain structure of [[Enoyl-Acyl-Carrier Protein Reductase]] with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZSN OCA].  
 
==See Also==
*[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16198563</ref><references group="xtra"/>
<ref group="xtra">PMID:016198563</ref><references group="xtra"/>
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Anderson, J W.]]
[[Category: Anderson, J W.]]
[[Category: Fidock, D A.]]
[[Category: Fidock, D A.]]
[[Category: Freundlich, J S.]]
[[Category: Freundlich, J S.]]
[[Category: Jacobs, W R.]]
[[Category: Jacobus, D P.]]
[[Category: Jacobus, D P.]]
[[Category: Jr., W R.Jacobs.]]
[[Category: Kuo, M.]]
[[Category: Kuo, M.]]
[[Category: Lucumi, E.]]
[[Category: Lucumi, E.]]
Line 38: Line 29:
[[Category: Yu, M.]]
[[Category: Yu, M.]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:15:36 2009''

Revision as of 07:27, 27 July 2012

File:1zsn.png

Template:STRUCTURE 1zsn

Synthesis, Biological Activity, and X-Ray Crystal Structural Analysis of Diaryl Ether Inhibitors of Malarial Enoyl ACP Reductase. Part 1:4'-Substituted Triclosan Derivatives

Template:ABSTRACT PUBMED 16198563

About this Structure

1zsn is a 2 chain structure of Enoyl-Acyl-Carrier Protein Reductase with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

See Also

Reference

  1. Freundlich JS, Anderson JW, Sarantakis D, Shieh HM, Yu M, Valderramos JC, Lucumi E, Kuo M, Jacobs WR Jr, Fidock DA, Schiehser GA, Jacobus DP, Sacchettini JC. Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5247-52. Epub 2005 Sep 29. PMID:16198563 doi:10.1016/j.bmcl.2005.08.044

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