3bu3: Difference between revisions

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{{Seed}}
[[Image:3bu3.png|left|200px]]
[[Image:3bu3.png|left|200px]]


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{{STRUCTURE_3bu3|  PDB=3bu3  |  SCENE=  }}  
{{STRUCTURE_3bu3|  PDB=3bu3  |  SCENE=  }}  


===Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide===
===Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide===


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The line below this paragraph, {{ABSTRACT_PUBMED_18278056}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_18278056}}
{{ABSTRACT_PUBMED_18278056}}


==Disease==
==About this Structure==
Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]]
[[3bu3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BU3 OCA].  


==About this Structure==
==See Also==
3BU3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BU3 OCA].
*[[Insulin receptor|Insulin receptor]]


==Reference==
==Reference==
<ref group="xtra">PMID:18278056</ref><references group="xtra"/>
<ref group="xtra">PMID:018278056</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Hubbard, S R.]]
[[Category: Hubbard, S R.]]
[[Category: Wu, J.]]
[[Category: Wu, J.]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
Line 45: Line 32:
[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Peptide]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Substrate]]
[[Category: Substrate]]
[[Category: Transducer]]
[[Category: Transducer]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:45:08 2009''

Revision as of 21:36, 7 January 2013

File:3bu3.png

Template:STRUCTURE 3bu3

Crystal structure of the insulin receptor kinase in complex with IRS2 KRLB peptide

Template:ABSTRACT PUBMED 18278056

About this Structure

3bu3 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wu J, Tseng YD, Xu CF, Neubert TA, White MF, Hubbard SR. Structural and biochemical characterization of the KRLB region in insulin receptor substrate-2. Nat Struct Mol Biol. 2008 Mar;15(3):251-8. Epub 2008 Feb 17. PMID:18278056 doi:10.1038/nsmb.1388

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