2gej: Difference between revisions

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[[Image:2gej.jpg|left|200px]]<br /><applet load="2gej" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:2gej.jpg|left|200px]]<br /><applet load="2gej" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2gej, resolution 2.600Å" />

'''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man'''<br />

==Overview==

Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for, mycobacterial growth that catalyses the first mannosylation step in, phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs, to the large GT4 family of glycosyltransferases, for which no structure is, currently available. Recombinant purified PimA from Mycobacterium, smegmatis has been crystallized in the presence of GDP and myo-inositol., The crystals belong to space group P2(1)2(1)2(1), with unit-cell, parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A, resolution.

Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for mycobacterial growth that catalyses the first mannosylation step in phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs to the large GT4 family of glycosyltransferases, for which no structure is currently available. Recombinant purified PimA from Mycobacterium smegmatis has been crystallized in the presence of GDP and myo-inositol. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A resolution.

==About this Structure==

2GEJ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] with GDD as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].

2GEJ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] with <scene name='pdbligand=GDD:'>GDD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].

==Reference==

Line 13:

[[Category: Mycobacterium smegmatis]]

[[Category: Protein complex]]

[[Category: Alzari, P.M.]]

[[Category: Alzari, P M.]]

[[Category: Buschiazzo, A.]]

[[Category: Guerin, M.E.]]

[[Category: Guerin, M E.]]

[[Category: Jackson, M.]]

[[Category: Kordulakova, J.]]

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[[Category: rossmann fold]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ 21 11:09:~~21 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:30:56 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2gej.jpg|left|200px]]<br /><applet load="2gej" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2gej.jpg|left|200px]]<br /><applet load="2gej" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2gej, resolution 2.600&Aring;" />
 '''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man'''<br />
 ==Overview==
-Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for, mycobacterial growth that catalyses the first mannosylation step in, phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs, to the large GT4 family of glycosyltransferases, for which no structure is, currently available. Recombinant purified PimA from Mycobacterium, smegmatis has been crystallized in the presence of GDP and myo-inositol., The crystals belong to space group P2(1)2(1)2(1), with unit-cell, parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A, resolution.
+Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for mycobacterial growth that catalyses the first mannosylation step in phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs to the large GT4 family of glycosyltransferases, for which no structure is currently available. Recombinant purified PimA from Mycobacterium smegmatis has been crystallized in the presence of GDP and myo-inositol. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A resolution.
 ==About this Structure==
-GEJ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] with GDD as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].
+GEJ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] with <scene name='pdbligand=GDD:'>GDD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Mycobacterium smegmatis]]
 [[Category: Protein complex]]
-[[Category: Alzari, P.M.]]
+[[Category: Alzari, P M.]]
 [[Category: Buschiazzo, A.]]
-[[Category: Guerin, M.E.]]
+[[Category: Guerin, M E.]]
 [[Category: Jackson, M.]]
 [[Category: Kordulakova, J.]]
@@ Line 24: / Line 24: @@
 [[Category: rossmann fold]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 11:09:21 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:30:56 2008''