3ctj: Difference between revisions
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[[Image:3ctj.png|left|200px]] | [[Image:3ctj.png|left|200px]] | ||
{{STRUCTURE_3ctj| PDB=3ctj | SCENE= }} | {{STRUCTURE_3ctj| PDB=3ctj | SCENE= }} | ||
===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met in complex with a aminopyridine based inhibitor=== | ===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met in complex with a aminopyridine based inhibitor=== | ||
{{ABSTRACT_PUBMED_18479916}} | {{ABSTRACT_PUBMED_18479916}} | ||
==About this Structure== | ==About this Structure== | ||
[[3ctj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CTJ OCA]. | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018479916</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
Revision as of 21:56, 7 January 2013
Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met in complex with a aminopyridine based inhibitor
Template:ABSTRACT PUBMED 18479916
About this Structure
3ctj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cai ZW, Wei D, Schroeder GM, Cornelius LA, Kim K, Chen XT, Schmidt RJ, Williams DK, Tokarski JS, An Y, Sack JS, Manne V, Kamath A, Zhang Y, Marathe P, Hunt JT, Lombardo LJ, Fargnoli J, Borzilleri RM. Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3224-9. Epub 2008 Apr 25. PMID:18479916 doi:10.1016/j.bmcl.2008.04.047