2ohp: Difference between revisions

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{{Seed}}
[[Image:2ohp.png|left|200px]]
[[Image:2ohp.png|left|200px]]


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{{STRUCTURE_2ohp|  PDB=2ohp  |  SCENE=  }}  
{{STRUCTURE_2ohp|  PDB=2ohp  |  SCENE=  }}  


===X-ray crystal structure of beta secretase complexed with compound 3===
===X-ray crystal structure of beta secretase complexed with compound 3===


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{{ABSTRACT_PUBMED_17315857}}
{{ABSTRACT_PUBMED_17315857}}


==About this Structure==
==About this Structure==
2OHP is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHP OCA].  
[[2ohp]] is a 1 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OHP OCA].  
 
==See Also==
*[[Beta secretase|Beta secretase]]


==Reference==
==Reference==
<ref group="xtra">PMID:17315857</ref><references group="xtra"/>
<ref group="xtra">PMID:017315857</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Patel, S.]]
[[Category: Patel, S.]]
[[Category: Alternative splicing]]
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Signal]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:37:31 2009''

Revision as of 09:15, 27 July 2012

File:2ohp.png

Template:STRUCTURE 2ohp

X-ray crystal structure of beta secretase complexed with compound 3

Template:ABSTRACT PUBMED 17315857

About this Structure

2ohp is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Congreve M, Aharony D, Albert J, Callaghan O, Campbell J, Carr RA, Chessari G, Cowan S, Edwards PD, Frederickson M, McMenamin R, Murray CW, Patel S, Wallis N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J Med Chem. 2007 Mar 22;50(6):1124-32. Epub 2007 Feb 22. PMID:17315857 doi:10.1021/jm061197u

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