1ld7: Difference between revisions

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{{Seed}}
[[Image:1ld7.png|left|200px]]
[[Image:1ld7.png|left|200px]]


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{{STRUCTURE_1ld7|  PDB=1ld7  |  SCENE=  }}  
{{STRUCTURE_1ld7|  PDB=1ld7  |  SCENE=  }}  


===Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66===
===Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66===


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{{ABSTRACT_PUBMED_12036349}}
{{ABSTRACT_PUBMED_12036349}}


==About this Structure==
==About this Structure==
1LD7 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD7 OCA].  
[[1ld7]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LD7 OCA].  
 
==See Also==
*[[Farnesyltransferase|Farnesyltransferase]]


==Reference==
==Reference==
<ref group="xtra">PMID:12036349</ref><references group="xtra"/>
<ref group="xtra">PMID:012036349</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
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[[Category: Pftase]]
[[Category: Pftase]]
[[Category: Ra]]
[[Category: Ra]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 02:47:14 2009''

Revision as of 09:24, 27 July 2012

File:1ld7.png

Template:STRUCTURE 1ld7

Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66

Template:ABSTRACT PUBMED 12036349

About this Structure

1ld7 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Bell IM, Gallicchio SN, Abrams M, Beese LS, Beshore DC, Bhimnathwala H, Bogusky MJ, Buser CA, Culberson JC, Davide J, Ellis-Hutchings M, Fernandes C, Gibbs JB, Graham SL, Hamilton KA, Hartman GD, Heimbrook DC, Homnick CF, Huber HE, Huff JR, Kassahun K, Koblan KS, Kohl NE, Lobell RB, Lynch JJ Jr, Robinson R, Rodrigues AD, Taylor JS, Walsh ES, Williams TM, Zartman CB. 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J Med Chem. 2002 Jun 6;45(12):2388-409. PMID:12036349

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