3c6t: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[3c6t]] is a 2 chain structure of [[Reverse transcriptase]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C6T OCA]. | |||
==See Also== | |||
*[[Reverse transcriptase]] | |||
==Reference== | ==Reference== | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
Revision as of 23:22, 26 December 2010
Crystal Structure of HIV Reverse Transcriptase in complex with inhibitor 14
Template:ABSTRACT PUBMED 18396399
About this Structure
3c6t is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.
See Also
Reference
- Tucker TJ, Saggar S, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Bioorg Med Chem Lett. 2008 May 1;18(9):2959-66. Epub 2008 Mar 25. PMID:18396399 doi:10.1016/j.bmcl.2008.03.064
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- Hiv-1 m:b hxb2r
- Prasad, S.
- Yan, Y.
- Aid
- Aspartyl protease
- Capsid maturation
- Capsid protein
- Cytoplasm
- Dna integration
- Dna recombination
- Dna-directed dna polymerase
- Endonuclease
- Hiv-1 reverse transcriptase
- Host-virus interaction
- Hydrolase
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- Nucleotidyltransferase
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- Zinc-finger