1u5b: Difference between revisions

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{{Seed}}
[[Image:1u5b.png|left|200px]]
[[Image:1u5b.png|left|200px]]


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{{STRUCTURE_1u5b|  PDB=1u5b  |  SCENE=  }}  
{{STRUCTURE_1u5b|  PDB=1u5b  |  SCENE=  }}  


===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===
===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===


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{{ABSTRACT_PUBMED_15576032}}
{{ABSTRACT_PUBMED_15576032}}
==Disease==
Known disease associated with this structure: Maple syrup urine disease, type Ia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608348 608348]], Maple syrup urine disease, type Ib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=248611 248611]]


==About this Structure==
==About this Structure==
1U5B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5B OCA].  
[[1u5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5B OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:15576032</ref><references group="xtra"/>
<ref group="xtra">PMID:015576032</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chuang, D T.]]
[[Category: Chuang, D T.]]
Line 38: Line 23:
[[Category: Branched-chain]]
[[Category: Branched-chain]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
[[Category: Ketoacid dehydrogenase]]
[[Category: Multi-enzyme complex]]
[[Category: Multi-enzyme complex]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
[[Category: Oxidoreductase,ketoacid dehydrogenase]]
[[Category: Oxidoreductase]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Thiamin diphosphate]]
[[Category: Thiamin diphosphate]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:03:25 2009''

Revision as of 11:42, 5 January 2013

File:1u5b.png

Template:STRUCTURE 1u5b

Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase

Template:ABSTRACT PUBMED 15576032

About this Structure

1u5b is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation. Structure. 2004 Dec;12(12):2185-96. PMID:15576032 doi:10.1016/j.str.2004.09.013

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