2qtl: Difference between revisions

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{{Seed}}
[[Image:2qtl.png|left|200px]]
[[Image:2qtl.png|left|200px]]


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{{STRUCTURE_2qtl|  PDB=2qtl  |  SCENE=  }}  
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===Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase===
===Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase===


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{{ABSTRACT_PUBMED_17892308}}
{{ABSTRACT_PUBMED_17892308}}
==Disease==
Known disease associated with this structure: Homocystinuria-megaloblastic anemia, cbl E type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602568 602568]], Neural tube defects, folate-sensitive, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=602568 602568]]


==About this Structure==
==About this Structure==
2QTL is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTL OCA].  
[[2qtl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QTL OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:17892308</ref><references group="xtra"/>
<ref group="xtra">PMID:017892308</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Leys, D.]]
[[Category: Leys, D.]]
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[[Category: Flexible hinge region]]
[[Category: Flexible hinge region]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:28:58 2009''

Revision as of 21:29, 7 January 2013

File:2qtl.png

Template:STRUCTURE 2qtl

Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase

Template:ABSTRACT PUBMED 17892308

About this Structure

2qtl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Wolthers KR, Lou X, Toogood HS, Leys D, Scrutton NS. Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry. Biochemistry. 2007 Oct 23;46(42):11833-44. Epub 2007 Sep 25. PMID:17892308 doi:10.1021/bi701209p

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