1e50: Difference between revisions

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==Disease==
==Disease==
Known disease associated with this structure: Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Platelet disorder, familial, with associated myeloid malignancy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]]
Known disease associated with this structure: Leukemia, acute myeloid OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Platelet disorder, familial, with associated myeloid malignancy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=151385 151385]], Myeloid leukemia, acute, M4Eo subtype OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=121360 121360]]


==About this Structure==
==About this Structure==
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[[Category: Warren, A J.]]
[[Category: Warren, A J.]]
[[Category: Williams, R L.]]
[[Category: Williams, R L.]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:51:11 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:12:42 2009''

Revision as of 15:12, 10 June 2009

File:1e50.png

Template:STRUCTURE 1e50

AML1/CBF COMPLEX

Template:ABSTRACT PUBMED 10856244

Disease

Known disease associated with this structure: Leukemia, acute myeloid OMIM:[151385], Platelet disorder, familial, with associated myeloid malignancy OMIM:[151385], Rheumatoid arthritis, susceptibility to OMIM:[151385], Myeloid leukemia, acute, M4Eo subtype OMIM:[121360]

About this Structure

1E50 is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta. EMBO J. 2000 Jun 15;19(12):3004-15. PMID:10856244 doi:10.1093/emboj/19.12.3004

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