3g1m: Difference between revisions

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New page: '''Unreleased structure''' The entry 3g1m is ON HOLD Authors: Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Pou...
 
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'''Unreleased structure'''
{{Seed}}
[[Image:3g1m.jpg|left|200px]]


The entry 3g1m is ON HOLD
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{{STRUCTURE_3g1m|  PDB=3g1m |  SCENE=  }}


Authors: Willand, N., Dirie, B., Carette, X., Bifani, P., Singhal, A., Desroses, M., Leroux, F., Willery, E., Mathys, V., Deprez-Poulain, R., Delcroix, G., Frenois, F., Aumercier, M., Locht, C., Villeret, V., Deprez, B., Baulard, A.R.
===EthR from Mycobacterium tuberculosis in complex with compound BDM31381===


Description: EthR from Mycobacterium tuberculosis in complex with compound BDM31381


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:54:14 2009''
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{{ABSTRACT_PUBMED_19412174}}
 
==About this Structure==
3G1M is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1M OCA].
 
==Reference==
<ref group="xtra">PMID:19412174</ref><ref group="xtra">PMID:16243584</ref><ref group="xtra">PMID:15494316</ref><ref group="xtra">PMID:14651620</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Aumercier, M.]]
[[Category: Baulard, A R.]]
[[Category: Bifani, P.]]
[[Category: Carette, X.]]
[[Category: Delcroix, G.]]
[[Category: Deprez, B.]]
[[Category: Deprez-Poulain, R.]]
[[Category: Desroses, M.]]
[[Category: Dirie, B.]]
[[Category: Frenois, F.]]
[[Category: Leroux, F.]]
[[Category: Locht, C.]]
[[Category: Mathys, V.]]
[[Category: Singhal, A.]]
[[Category: Villeret, V.]]
[[Category: Willand, N.]]
[[Category: Willery, E.]]
[[Category: Dna-binding]]
[[Category: Tetr family]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:36:10 2009''

Revision as of 17:36, 22 July 2009

File:3g1m.jpg

Template:STRUCTURE 3g1m

EthR from Mycobacterium tuberculosis in complex with compound BDM31381

Template:ABSTRACT PUBMED 19412174

About this Structure

3G1M is a 1 chain structure of sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  1. Willand N, Dirie B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Deprez-Poulain R, Delcroix G, Frenois F, Aumercier M, Locht C, Villeret V, Deprez B, Baulard AR. Synthetic EthR inhibitors boost antituberculous activity of ethionamide. Nat Med. 2009 May;15(5):537-44. Epub 2009 May 3. PMID:19412174 doi:10.1038/nm.1950
  2. Frenois F, Baulard AR, Villeret V. Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis. Tuberculosis (Edinb). 2006 Mar;86(2):110-4. Epub 2005 Oct 21. PMID:16243584 doi:10.1016/j.tube.2005.07.005
  3. Frenois F, Engohang-Ndong J, Locht C, Baulard AR, Villeret V. Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis. Mol Cell. 2004 Oct 22;16(2):301-7. PMID:15494316 doi:10.1016/j.molcel.2004.09.020
  4. Engohang-Ndong J, Baillat D, Aumercier M, Bellefontaine F, Besra GS, Locht C, Baulard AR. EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator. Mol Microbiol. 2004 Jan;51(1):175-88. PMID:14651620

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