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{{Seed}}
[[Image:1sej.png|left|200px]]
[[Image:1sej.png|left|200px]]


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===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP===
===Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP===


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{{ABSTRACT_PUBMED_16511011}}


==About this Structure==
==About this Structure==
1SEJ is a 5 chains structure of sequences from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEJ OCA].  
[[1sej]] is a 5 chain structure of [[Dihydrofolate reductase]] and [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_hominis Cryptosporidium hominis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEJ OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Thymidylate synthase|Thymidylate synthase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16511011</ref><references group="xtra"/>
<ref group="xtra">PMID:016511011</ref><references group="xtra"/>
[[Category: Cryptosporidium hominis]]
[[Category: Cryptosporidium hominis]]
[[Category: Anderson, A C.]]
[[Category: Anderson, A C.]]
[[Category: Bifunctional enzyme]]
[[Category: Bifunctional enzyme]]
 
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:17:18 2009''
[[Category: Transferase]]

Revision as of 15:31, 27 July 2012

File:1sej.png

Template:STRUCTURE 1sej

Crystal Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis Bound to 1843U89/NADPH/dUMP

Template:ABSTRACT PUBMED 16511011

About this Structure

1sej is a 5 chain structure of Dihydrofolate reductase and Thymidylate synthase with sequence from Cryptosporidium hominis. Full crystallographic information is available from OCA.

See Also

Reference

  1. Anderson AC. Two crystal structures of dihydrofolate reductase-thymidylate synthase from Cryptosporidium hominis reveal protein-ligand interactions including a structural basis for observed antifolate resistance. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Mar 1;61(Pt, 3):258-62. Epub 2005 Feb 8. PMID:16511011 doi:10.1107/S1744309105002435

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