3pva: Difference between revisions
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{{STRUCTURE_3pva| PDB=3pva | SCENE= }} | {{STRUCTURE_3pva| PDB=3pva | SCENE= }} | ||
===PENICILLIN V ACYLASE FROM B. SPHAERICUS=== | ===PENICILLIN V ACYLASE FROM B. SPHAERICUS=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/PAC_BACSH PAC_BACSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase. | |||
==About this Structure== | ==About this Structure== | ||
[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. | |||
==See Also== | |||
*[[Penicillin acylase|Penicillin acylase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:010331865</ref><references group="xtra"/><references/> | ||
[[Category: Lysinibacillus sphaericus]] | [[Category: Lysinibacillus sphaericus]] | ||
[[Category: Penicillin amidase]] | [[Category: Penicillin amidase]] | ||
| Line 31: | Line 26: | ||
[[Category: Verma, C S.]] | [[Category: Verma, C S.]] | ||
[[Category: Amidohydrolase]] | [[Category: Amidohydrolase]] | ||
[[Category: Hydrolase]] | |||
[[Category: Ntn hydrolase]] | [[Category: Ntn hydrolase]] | ||
[[Category: Penicillin v acylase]] | [[Category: Penicillin v acylase]] | ||
Revision as of 08:36, 8 May 2013
PENICILLIN V ACYLASE FROM B. SPHAERICUS
Function
[PAC_BACSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
About this Structure
3pva is a 8 chain structure with sequence from Lysinibacillus sphaericus. Full crystallographic information is available from OCA.
See Also
Reference
- Suresh CG, Pundle AV, SivaRaman H, Rao KN, Brannigan JA, McVey CE, Verma CS, Dauter Z, Dodson EJ, Dodson GG. Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members. Nat Struct Biol. 1999 May;6(5):414-6. PMID:10331865 doi:10.1038/8213
