1ia2: Difference between revisions

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{{Seed}}
[[Image:1ia2.png|left|200px]]
[[Image:1ia2.png|left|200px]]


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{{STRUCTURE_1ia2|  PDB=1ia2  |  SCENE=  }}  
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===Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW578)===
===Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW578)===


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{{ABSTRACT_PUBMED_11520201}}
{{ABSTRACT_PUBMED_11520201}}


==About this Structure==
==About this Structure==
1IA2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA2 OCA].  
[[1ia2]] is a 2 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Candida_albicans Candida albicans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IA2 OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:11520201</ref><references group="xtra"/>
<ref group="xtra">PMID:011520201</ref><references group="xtra"/>
[[Category: Candida albicans]]
[[Category: Candida albicans]]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Reductase]]
[[Category: Reductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:50:08 2009''

Revision as of 16:16, 27 July 2012

File:1ia2.png

Template:STRUCTURE 1ia2

Candida albicans dihydrofolate reductase complexed with dihydro-nicotinamide-adenine-dinucleotide phosphate (NADPH) and 5-[(4-METHYLPHENYL)SULFANYL]-2,4-QUINAZOLINEDIAMINE (GW578)

Template:ABSTRACT PUBMED 11520201

About this Structure

1ia2 is a 2 chain structure of Dihydrofolate reductase with sequence from Candida albicans. Full crystallographic information is available from OCA.

See Also

Reference

  1. Whitlow M, Howard AJ, Stewart D, Hardman KD, Chan JH, Baccanari DP, Tansik RL, Hong JS, Kuyper LF. X-Ray crystal structures of Candida albicans dihydrofolate reductase: high resolution ternary complexes in which the dihydronicotinamide moiety of NADPH is displaced by an inhibitor. J Med Chem. 2001 Aug 30;44(18):2928-32. PMID:11520201

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