2hog: Difference between revisions

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{{Seed}}
[[Image:2hog.png|left|200px]]
[[Image:2hog.png|left|200px]]


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{{STRUCTURE_2hog|  PDB=2hog  |  SCENE=  }}  
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===crystal structure of Chek1 in complex with inhibitor 20===
===crystal structure of Chek1 in complex with inhibitor 20===


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{{ABSTRACT_PUBMED_16978863}}
{{ABSTRACT_PUBMED_16978863}}


==About this Structure==
==About this Structure==
2HOG is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HOG OCA].  
[[2hog]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HOG OCA].  
 
==See Also==
*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]


==Reference==
==Reference==
<ref group="xtra">PMID:16978863</ref><references group="xtra"/>
<ref group="xtra">PMID:016978863</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Chek1]]
[[Category: Chek1]]
[[Category: Kinase]]
[[Category: Kinase]]
 
[[Category: Transferase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:54:08 2009''

Revision as of 16:23, 27 July 2012

File:2hog.png

Template:STRUCTURE 2hog

crystal structure of Chek1 in complex with inhibitor 20

Template:ABSTRACT PUBMED 16978863

About this Structure

2hog is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Fraley ME, Steen JT, Brnardic EJ, Arrington KL, Spencer KL, Hanney BA, Kim Y, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W, Beck SC, Mao X, Lobell RB, Sepp-Lorenzino L, Yan Y, Ikuta M, Munshi SK, Kuo LC, Kreatsoulas C. 3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6049-53. Epub 2006 Sep 15. PMID:16978863 doi:10.1016/j.bmcl.2006.08.118

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