3cen: Difference between revisions

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{{Seed}}
[[Image:3cen.png|left|200px]]
[[Image:3cen.png|left|200px]]


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{{STRUCTURE_3cen|  PDB=3cen  |  SCENE=  }}  
{{STRUCTURE_3cen|  PDB=3cen  |  SCENE=  }}  


===Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide===
===Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide===


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{{ABSTRACT_PUBMED_18424044}}
{{ABSTRACT_PUBMED_18424044}}


==About this Structure==
==About this Structure==
3CEN is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEN OCA].  
[[3cen]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CEN OCA].  
 
==See Also==
*[[Factor Xa|Factor Xa]]


==Reference==
==Reference==
<ref group="xtra">PMID:18424044</ref><references group="xtra"/>
<ref group="xtra">PMID:018424044</ref><references group="xtra"/>
[[Category: Coagulation factor Xa]]
[[Category: Coagulation factor Xa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
[[Category: Plasma]]
[[Category: Plasma]]
[[Category: Polymorphism]]
[[Category: Protein inhibitor complex]]
[[Category: Protein inhibitor complex]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:56:14 2009''

Revision as of 16:26, 27 July 2012

File:3cen.png

Template:STRUCTURE 3cen

Factor XA in complex with the inhibitor N-(2-(((5-chloro-2-pyridinyl) amino)sulfonyl)phenyl)-4-(2-oxo-1(2H)-pyridinyl)benzamide

Template:ABSTRACT PUBMED 18424044

About this Structure

3cen is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Corte JR, Fang T, Pinto DJ, Han W, Hu Z, Jiang XJ, Li YL, Gauuan JF, Hadden M, Orton D, Rendina AR, Luettgen JM, Wong PC, He K, Morin PE, Chang CH, Cheney DL, Knabb RM, Wexler RR, Lam PY. Structure-activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties. Bioorg Med Chem Lett. 2008 May 1;18(9):2845-9. Epub 2008 Apr 8. PMID:18424044 doi:10.1016/j.bmcl.2008.03.092

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