2j01: Difference between revisions

Line 1:

[[Image:2j01.gif|left|200px]]<br /><applet load="2j01" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:2j01.gif|left|200px]]<br /><applet load="2j01" size="350" color="white" frame="true" align="right" spinBox="true"

caption="2j01, resolution 2.8Å" />

'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.'''<br />

==Overview==

The crystal structure of the bacterial 70S ribosome refined to 2.8, angstrom resolution reveals atomic details of its interactions with, messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a, kink in the mRNA that demarcates the boundary between A and P sites, which, is potentially important to prevent slippage of mRNA. Metal ions also, stabilize the intersubunit interface. The interactions of E-site tRNA with, the 50S subunit have both similarities and differences compared to those, in the archaeal ribosome. The structure also rationalizes much biochemical, and genetic data on translation.

The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.

==About this Structure==

2J01 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=2J01 OCA].

2J01 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J01 OCA].

==Reference==

Line 13:

[[Category: Protein complex]]

[[Category: Thermus thermophilus]]

[[Category: Dunham, C.M.]]

[[Category: Dunham, C M.]]

[[Category: Kelley, A.C.]]

[[Category: Kelley, A C.]]

[[Category: Murphy, F.V.]]

[[Category: Murphy, F V.]]

[[Category: Petry, S.]]

[[Category: Ramakrishnan, V.]]

[[Category: Selmer, M.]]

[[Category: Weir, J.R.]]

[[Category: Weir, J R.]]

[[Category: Weixlbaumer, A.]]

[[Category: mrna]]

Line 27:

[[Category: trna]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Wed Nov~~ 21 12:29:~~44 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:57:49 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2j01.gif|left|200px]]<br /><applet load="2j01" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:2j01.gif|left|200px]]<br /><applet load="2j01" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="2j01, resolution 2.8&Aring;" />
 '''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.'''<br />
 ==Overview==
-The crystal structure of the bacterial 70S ribosome refined to 2.8, angstrom resolution reveals atomic details of its interactions with, messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a, kink in the mRNA that demarcates the boundary between A and P sites, which, is potentially important to prevent slippage of mRNA. Metal ions also, stabilize the intersubunit interface. The interactions of E-site tRNA with, the 50S subunit have both similarities and differences compared to those, in the archaeal ribosome. The structure also rationalizes much biochemical, and genetic data on translation.
+The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.
 ==About this Structure==
-J01 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J01 OCA].
+J01 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J01 OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Protein complex]]
 [[Category: Thermus thermophilus]]
-[[Category: Dunham, C.M.]]
+[[Category: Dunham, C M.]]
-[[Category: Kelley, A.C.]]
+[[Category: Kelley, A C.]]
-[[Category: Murphy, F.V.]]
+[[Category: Murphy, F V.]]
 [[Category: Petry, S.]]
 [[Category: Ramakrishnan, V.]]
 [[Category: Selmer, M.]]
-[[Category: Weir, J.R.]]
+[[Category: Weir, J R.]]
 [[Category: Weixlbaumer, A.]]
 [[Category: mrna]]
@@ Line 27: / Line 27: @@
 [[Category: trna]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 12:29:44 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:57:49 2008''