3fxi: Difference between revisions

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{{Seed}}
{{Seed}}
[[Image:3fxi.jpg|left|200px]]
[[Image:3fxi.png|left|200px]]


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===Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex===
===Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex===


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{{ABSTRACT_PUBMED_19252480}}


==Disease==
==Disease==
Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Colorectal cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Longevity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Macular degeneration, age-related, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]]
Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Colorectal cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]], Macular degeneration, age-related, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=603030 603030]]


==About this Structure==
==About this Structure==
3FXI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FXI OCA].  
3FXI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FXI OCA].  
==Reference==
<ref group="xtra">PMID:19252480</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar  4 14:57:51 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:03:42 2009''

Revision as of 06:03, 13 May 2009

File:3fxi.png

Template:STRUCTURE 3fxi

Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

Template:ABSTRACT PUBMED 19252480

Disease

Known disease associated with this structure: Endotoxin hyporesponsiveness OMIM:[603030], Colorectal cancer, susceptibility to OMIM:[603030], Macular degeneration, age-related, 10 OMIM:[603030]

About this Structure

3FXI is a 4 chains structure of sequences from Escherichia coli and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830

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