3e88: Difference between revisions

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{{Seed}}
[[Image:3e88.png|left|200px]]
[[Image:3e88.png|left|200px]]


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{{ABSTRACT_PUBMED_19179070}}
{{ABSTRACT_PUBMED_19179070}}
==Disease==
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164731 164731]]


==About this Structure==
==About this Structure==
3E88 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E88 OCA].  
[[3e88]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E88 OCA].  


==Reference==
==Reference==
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[[Category: Smallwood, A.]]
[[Category: Smallwood, A.]]
[[Category: Ward, P.]]
[[Category: Ward, P.]]
[[Category: Akt2]]
[[Category: Alternative splicing]]
[[Category: Atp-binding]]
[[Category: Gsk3 beta]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Wnt signaling pathway]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:30:48 2009''

Revision as of 09:56, 21 April 2011

File:3e88.png

Template:STRUCTURE 3e88

Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

Template:ABSTRACT PUBMED 19179070

About this Structure

3e88 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Rouse MB, Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA. Aminofurazans as potent inhibitors of AKT kinase. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9. PMID:19179070 doi:10.1016/j.bmcl.2009.01.002

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