2jc0: Difference between revisions
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[[Image:2jc0.png|left|200px]] | [[Image:2jc0.png|left|200px]] | ||
{{STRUCTURE_2jc0| PDB=2jc0 | SCENE= }} | {{STRUCTURE_2jc0| PDB=2jc0 | SCENE= }} | ||
===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264=== | ===CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264=== | ||
{{ABSTRACT_PUBMED_17269759}} | {{ABSTRACT_PUBMED_17269759}} | ||
==About this Structure== | ==About this Structure== | ||
[[2jc0]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JC0 OCA]. | |||
==See Also== | |||
*[[RNA polymerase|RNA polymerase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:017269759</ref><references group="xtra"/> | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: Singh, O M.]] | [[Category: Singh, O M.]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Polymerase]] | [[Category: Polymerase]] | ||
Revision as of 13:40, 25 July 2012
CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264
Template:ABSTRACT PUBMED 17269759
About this Structure
2jc0 is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Slater MJ, Amphlett EM, Andrews DM, Bravi G, Burton G, Cheasty AG, Corfield JA, Ellis MR, Fenwick RH, Fernandes S, Guidetti R, Haigh D, Hartley CD, Howes PD, Jackson DL, Jarvest RL, Lovegrove VL, Medhurst KJ, Parry NR, Price H, Shah P, Singh OM, Stocker R, Thommes P, Wilkinson C, Wonacott A. Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate. J Med Chem. 2007 Mar 8;50(5):897-900. Epub 2007 Feb 2. PMID:17269759 doi:10.1021/jm061207r