3cog: Difference between revisions

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{{Seed}}
[[Image:3cog.png|left|200px]]
[[Image:3cog.png|left|200px]]


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===Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine===
===Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine===


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{{ABSTRACT_PUBMED_19019829}}
{{ABSTRACT_PUBMED_19019829}}
==Disease==
Known disease associated with this structure: Cystathioninuria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607657 607657]], Homocysteine, total plasma, elevated OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607657 607657]]


==About this Structure==
==About this Structure==
3COG is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COG OCA].  
[[3cog]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3COG OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19019829</ref><references group="xtra"/>
<ref group="xtra">PMID:019019829</ref><references group="xtra"/>
[[Category: Cystathionine gamma-lyase]]
[[Category: Cystathionine gamma-lyase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Welin, M.]]
[[Category: Welin, M.]]
[[Category: Wikstrom, M.]]
[[Category: Wikstrom, M.]]
[[Category: Alternative splicing]]
[[Category: Amino-acid biosynthesis]]
[[Category: Amino-acid biosynthesis]]
[[Category: Cth]]
[[Category: Cth]]
[[Category: Cysteine biosynthesis]]
[[Category: Cysteine biosynthesis]]
[[Category: Cytoplasm]]
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Inhibitor]]
[[Category: Inhibitor]]
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Plp]]
[[Category: Plp]]
[[Category: Polymorphism]]
[[Category: Propargylglycine]]
[[Category: Propargylglycine]]
[[Category: Pyridoxal phosphate]]
[[Category: Pyridoxal phosphate]]
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[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  2 15:28:12 2009''

Revision as of 18:00, 7 January 2013

File:3cog.png

Template:STRUCTURE 3cog

Crystal structure of human cystathionase (Cystathionine gamma lyase) in complex with DL-propargylglycine

Template:ABSTRACT PUBMED 19019829

About this Structure

3cog is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sun Q, Collins R, Huang S, Holmberg-Schiavone L, Anand GS, Tan CH, van-den-Berg S, Deng LW, Moore PK, Karlberg T, Sivaraman J. Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S. J Biol Chem. 2009 Jan 30;284(5):3076-85. Epub 2008 Nov 19. PMID:19019829 doi:https://dx.doi.org/10.1074/jbc.M805459200

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