NS5B: Difference between revisions

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[[Image:1NB4_4domains.jpg]]
[[Image:1NB4_4domains.jpg]]


<applet load='2HAI_DNA5.pdb' size='400' frame='true' align='right' caption='Insert caption here' />
<applet load='2HAI_DNA5.pdb' size='400' frame='true' align='right' caption='PDB IDs 2HAI (protein) 1RTD (DNA)' />NS5B with B form DNA from HIV Reverse Transcriptase co-crystal model.  DNA was modeled in by alignment of palms domain. A beta hairpin in the thumb domain has been moved to accommodate DNA, the hairpin is modeled into the minor groove, a possible binding site.

Revision as of 06:02, 20 April 2009

NS5B, the RNA Dependent RNA Polymerase from Hepatitis C Virus

PDB ID 2HAI

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File:1NB4 4domains.jpg

PDB IDs 2HAI (protein) 1RTD (DNA)

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NS5B with B form DNA from HIV Reverse Transcriptase co-crystal model. DNA was modeled in by alignment of palms domain. A beta hairpin in the thumb domain has been moved to accommodate DNA, the hairpin is modeled into the minor groove, a possible binding site.