3fqf: Difference between revisions

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{{Seed}}
[[Image:3fqf.png|left|200px]]
[[Image:3fqf.png|left|200px]]


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{{STRUCTURE_3fqf|  PDB=3fqf  |  SCENE=  }}  
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===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)===
===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)===


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{{ABSTRACT_PUBMED_19249312}}
{{ABSTRACT_PUBMED_19249312}}


==About this Structure==
==About this Structure==
3FQF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQF OCA].  
[[3fqf]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQF OCA].  
 
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]


==Reference==
==Reference==
<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
<ref group="xtra">PMID:019249312</ref><references group="xtra"/>
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Staphylococcus aureus rf122]]
[[Category: Staphylococcus aureus rf122]]
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[[Category: Lombardo, M N.]]
[[Category: Lombardo, M N.]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 10:38:41 2009''

Revision as of 05:16, 26 July 2012

File:3fqf.png

Template:STRUCTURE 3fqf

Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)

Template:ABSTRACT PUBMED 19249312

About this Structure

3fqf is a 1 chain structure of Dihydrofolate reductase with sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

See Also

Reference

  1. Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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