3dd1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
[[Image:3dd1. | [[Image:3dd1.png|left|200px]] | ||
<!-- | <!-- | ||
| Line 45: | Line 45: | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 10:26:16 2009'' | ||
Revision as of 07:26, 6 May 2009
Crystal structure of glycogen phophorylase complexed with an anthranilimide based inhibitor GSK254
Template:ABSTRACT PUBMED 19138846
Disease
Known disease associated with this structure: Glycogen storage disease VI OMIM:[232700]
About this Structure
3DD1 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Thomson SA, Banker P, Bickett DM, Boucheron JA, Carter HL, Clancy DC, Cooper JP, Dickerson SH, Garrido DM, Nolte RT, Peat AJ, Sheckler LR, Sparks SM, Tavares FX, Wang L, Wang TY, Weiel JE. Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1177-82. Epub 2008 Dec 25. PMID:19138846 doi:10.1016/j.bmcl.2008.12.085
Page seeded by OCA on Wed May 6 10:26:16 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Phosphorylase
- Nolte, R T.
- Acetylation
- Allosteric enzyme
- Carbohydrate metabolism
- Diabetes
- Disease mutation
- Glycogen metabolism
- Glycogen phosphorylase hlgp
- Glycogen storage disease
- Glycosyltransferase
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Pyridoxal phosphate
- Transferase
