Factor IX: Difference between revisions

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http://www.molecular-haemostasis.de/grfx/pix/
 


The post-translational modification of the glutamic acid residues of the FIX polypeptide is carried out by vitamin K-dependent  -glutamyl carboxylase (1). Vitamin K-dependent carboxylase is a membrane associated protein in the endoplasmic reticulum. It converts a multiple of glutamic acid residues which are located within 40 residues of a propeptide-containing sequence into  - carboxyglutamate (2).
The post-translational modification of the glutamic acid residues of the FIX polypeptide is carried out by vitamin K-dependent  -glutamyl carboxylase (1). Vitamin K-dependent carboxylase is a membrane associated protein in the endoplasmic reticulum. It converts a multiple of glutamic acid residues which are located within 40 residues of a propeptide-containing sequence into  - carboxyglutamate (2).