Factor IX: Difference between revisions
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Step 1: Vitamin K is in its active hydroquinone form: In this reaction a proton (H+ ion) is removed from the glutamic acid in an oxygen (O2) consuming reaction. This reaction leads to a carbon ion aring on the glutamic acid molecule. | Step 1: Vitamin K is in its active hydroquinone form: In this reaction a proton (H+ ion) is removed from the glutamic acid in an oxygen (O2) consuming reaction. This reaction leads to a carbon ion aring on the glutamic acid molecule. | ||
Step 2: The glutamic acid carbon ion reacts with CO2 forming gamma-carboxyglutamate. | Step 2: The glutamic acid carbon ion reacts with CO2 forming gamma-carboxyglutamate. | ||
Step 3 and 4: Active vitamin K in the hydroquinone form is regenerated in two reaction step. | |||
Step 3 and 4: Active vitamin K in the hydroquinone form is regenerated in two reaction step. | |||