Factor IX: Difference between revisions

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Step 1: Vitamin K is in its active hydroquinone form: In this reaction a proton (H+ ion)  is removed from the glutamic acid in an oxygen (O2) consuming reaction. This reaction leads to a carbon ion aring on the glutamic acid molecule.  
Step 1: Vitamin K is in its active hydroquinone form: In this reaction a proton (H+ ion)  is removed from the glutamic acid in an oxygen (O2) consuming reaction. This reaction leads to a carbon ion aring on the glutamic acid molecule.  
Step 2: The glutamic acid carbon ion reacts with CO2 forming gamma-carboxyglutamate.  
Step 2: The glutamic acid carbon ion reacts with CO2 forming gamma-carboxyglutamate.  
Step 3 and 4: Active vitamin K in the hydroquinone form is regenerated in two reaction step.  
 
 
Step 3 and 4: Active vitamin K in the hydroquinone form is regenerated in two reaction step.