3gcw: Difference between revisions

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{{Seed}}
[[Image:3gcw.png|left|200px]]
[[Image:3gcw.png|left|200px]]


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{{STRUCTURE_3gcw|  PDB=3gcw  |  SCENE=  }}  
{{STRUCTURE_3gcw|  PDB=3gcw  |  SCENE=  }}  


===PCSK9:EGFA(H306Y)===
===PCSK9:EGFA(H306Y)===


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{{ABSTRACT_PUBMED_19224862}}
{{ABSTRACT_PUBMED_19224862}}
==Disease==
Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606945 606945]]


==About this Structure==
==About this Structure==
3GCW is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCW OCA].  
[[3gcw]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GCW OCA].  


==Reference==
==Reference==
<ref group="xtra">PMID:19224862</ref><references group="xtra"/>
<ref group="xtra">PMID:019224862</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kwon, H J.]]
[[Category: Kwon, H J.]]
[[Category: Alternative splicing]]
[[Category: Autocatalytic cleavage]]
[[Category: Autocatalytic cleavage]]
[[Category: Calcium]]
[[Category: Cholesterol metabolism]]
[[Category: Cholesterol metabolism]]
[[Category: Coated pit]]
[[Category: Coated pit]]
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[[Category: Pcsk9]]
[[Category: Pcsk9]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Protease]]
[[Category: Protein binding]]
[[Category: Protein binding]]
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[[Category: Transport]]
[[Category: Transport]]
[[Category: Zymogen]]
[[Category: Zymogen]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 29 20:56:24 2009''

Revision as of 14:47, 20 February 2013

File:3gcw.png

Template:STRUCTURE 3gcw

PCSK9:EGFA(H306Y)

Template:ABSTRACT PUBMED 19224862

About this Structure

3gcw is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem. 2009 Apr 17;284(16):10561-70. Epub 2009 Feb 17. PMID:19224862 doi:10.1074/jbc.M808802200

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