3h3c: Difference between revisions
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===Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog=== | |||
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{{ABSTRACT_PUBMED_19428251}} | |||
==About this Structure== | |||
3H3C is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H3C OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19428251</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific protein-tyrosine kinase]] | |||
[[Category: Han, S.]] | |||
[[Category: Mistry, A.]] | |||
[[Category: Alternative splicing]] | |||
[[Category: Atp-binding]] | |||
[[Category: Cell membrane]] | |||
[[Category: Cytoplasm]] | |||
[[Category: Kinase]] | |||
[[Category: Membrane]] | |||
[[Category: Nucleotide-binding]] | |||
[[Category: Phosphoprotein]] | |||
[[Category: Polymorphism]] | |||
[[Category: Pyk2]] | |||
[[Category: Transferase]] | |||
[[Category: Tyrosine-protein kinase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 27 15:23:29 2009'' | |||
Revision as of 12:23, 27 May 2009
Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog
Template:ABSTRACT PUBMED 19428251
About this Structure
3H3C is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Walker DP, Zawistoski MP, McGlynn MA, Li JC, Kung DW, Bonnette PC, Baumann A, Buckbinder L, Houser JA, Boer J, Mistry A, Han S, Xing L, Guzman-Perez A. Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3253-8. Epub 2009 Apr 24. PMID:19428251 doi:10.1016/j.bmcl.2009.04.093
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