Sandbox1313: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Mark Omobono (talk | contribs) |
Mark Omobono (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_1bbw| PDB=1bbw | SCENE= }} | {{STRUCTURE_1bbw| PDB=1bbw | SCENE= }} | ||
| Line 8: | Line 7: | ||
In the active site, the bound lysine participates in multiple hydrogen bonding interactions to stay complexed to the synthase protein as it moves into position to build the tRNA in the ribosome. Specifically, | In the active site, the bound lysine participates in multiple hydrogen bonding interactions to stay complexed to the synthase protein as it moves into position to build the tRNA in the ribosome. Specifically, | ||
<scene name='Sandbox1313/Hydrogen_bonding_partners/1'>these residues</scene> trigger a complex conformational change that completely changes the shape of part of the synthase. These changes involve <scene name='Sandbox1313/These_two_loops/1'>these two loops</scene> and some <scene name='Sandbox1313/Other_pieces/ | <scene name='Sandbox1313/Hydrogen_bonding_partners/1'>these residues</scene> trigger a complex conformational change that completely changes the shape of part of the synthase. These changes involve <scene name='Sandbox1313/These_two_loops/1'>these two loops</scene> and some <scene name='Sandbox1313/Other_pieces/2'>other pieces</scene> of the molecule. This conformational change effectively closes the active site when bound to lysine. | ||
