Sandbox 5: Difference between revisions
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== The Oxygenase domain of NOS == | == The Oxygenase domain of NOS == | ||
The <scene name='Sandbox_5/Nos_oxygenase_med_cofaktore/3'>oxygenase domain</scene> contains the active site of the enzyme. The active site binds the substrate L-<scene name='Sandbox_5/Nos_oxygenase_arg/2'>Arginine</scene> ([http://en.wikipedia.org/wiki/Arginine Arginine]) and is converted into citruline and NO (explained in details below). The domain has three cofactors bound: | |||
<scene name='Sandbox_5/ | <scene name='Sandbox_5/Nos_oxygenase_bh4/2'>BH4</scene> ([http://en.wikipedia.org/wiki/BH4 (6R).5,6,7,8-Tetrahydrobiopterin]) | ||
<scene name='Sandbox_5/ | <scene name='Sandbox_5/Nos_oxygenase_heme/2'>Heme</scene>([http://en.wikipedia.org/wiki/Heme Heme]) | ||
and a Zinc ion. | |||
An electron is passed on from the reductase domain to the Heme group, | |||
== The Reductase Domain of NOS == | == The Reductase Domain of NOS == | ||
