Sandbox1111: Difference between revisions

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<scene name='Sandbox1111/Polar_bonds/1'>Polar bonds</scene> in dark green
<scene name='Sandbox1111/Polar_bonds/1'>Polar bonds</scene> in dark green
<scene name='Sandbox1111/Active_sites/1'>Active Sites</scene> are shown in brown


==Reference==
==Reference==


Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196
Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196

Revision as of 03:51, 22 May 2009

This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!

Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

By Amit Shavit


Drag the structure with the mouse to rotate
3cin, resolution 1.70Å (default scene)
Ligands: CL, MG, NAD
Gene: TM1419, TM_1419 (Thermotoga maritima MSB8)
Activity: Inositol-3-phosphate synthase, with EC number 5.5.1.4
Resources: FirstGlance, OCA, RCSB, PDBsum, TOPSAN
Coordinates: save as pdb, mmCIF, xml



Protein

Active Sites are shown in brown

Structure

Beta Sheet are portrayed in purple.

Alpha Helices are portrayed in blue

Hydrophobic interactions in red

Polar bonds in dark green

Active Sites are shown in brown

Reference

Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196