Epitopes: Difference between revisions

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===T Lymphocyte Epitopes===
===T Lymphocyte Epitopes===
It is unfortunate that ''epitope'' has caught on as the term to describe the peptide fragments that T cells recognize, since these are not necessarily derived from the surfaces of protein antigens, but may be derived from portions that were buried in the folded protein. While the perhaps better terms ''cryptotope'' and ''unfoldon'' are almost never used, they illustrate the point.
It is unfortunate that ''epitope'' has caught on as the term to describe the peptide fragments that T cells recognize, since these are not necessarily derived from the surfaces of protein antigens, but may be derived from portions that were buried in the folded protein. The terms ''cryptotope'' and ''unfoldon'' are almost never used, but are perhaps more descriptive.


==Characteristics==
==Characteristics==