Nitric Oxide Synthase: Difference between revisions
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The active site is highly conserved in the different NOS species. Thus it is possible to discuss substrate binding i general terms. The NOS enzyme binds its substrate by hydrogen bindings both to the guanidino[http://en.wikipedia.org/wiki/Guanidino] end and the amino acid end (EVT FIG!). | The active site is highly conserved in the different NOS species. Thus it is possible to discuss substrate binding i general terms. The NOS enzyme binds its substrate by hydrogen bindings both to the guanidino[http://en.wikipedia.org/wiki/Guanidino] end and the amino acid end (EVT FIG!). | ||
<scene name=' | <scene name='Nitric_oxide_synthase/Substratebinding_test/1'>Substrate in catalytic site</scene> | ||
binds its substrate (L-arginine) by coordinating CO to the heme at the site occupied by oxygen....<ref>PMID:9376373 </ref>. | binds its substrate (L-arginine) by coordinating CO to the heme at the site occupied by oxygen....<ref>PMID:9376373 </ref>. | ||
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===H<sub>4</sub>B=== | ===H<sub>4</sub>B=== | ||
[[image:bh4.png|left|frame|Structure of tetrahydrobiopterin]] | [[image:bh4.png|left|frame|Structure of tetrahydrobiopterin]] | ||
