3edz: Difference between revisions
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[[Image:3edz.png|left|200px]] | [[Image:3edz.png|left|200px]] | ||
{{STRUCTURE_3edz| PDB=3edz | SCENE= }} | {{STRUCTURE_3edz| PDB=3edz | SCENE= }} | ||
===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor=== | ===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor=== | ||
{{ABSTRACT_PUBMED_18835710}} | {{ABSTRACT_PUBMED_18835710}} | ||
==About this Structure== | ==About this Structure== | ||
[[3edz]] is a 2 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EDZ OCA]. | |||
==See Also== | |||
*[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:018835710</ref><references group="xtra"/> | ||
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| Line 41: | Line 32: | ||
[[Category: Zhou, G.]] | [[Category: Zhou, G.]] | ||
[[Category: Zhu, Z.]] | [[Category: Zhu, Z.]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| Line 53: | Line 43: | ||
[[Category: Sh3-binding]] | [[Category: Sh3-binding]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zn-endopeptidase]] | [[Category: Zn-endopeptidase]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 19:46, 26 July 2012
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3edz is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- ADAM 17 endopeptidase
- Homo sapiens
- Guo, Z.
- Kozlowski, J.
- Lavey, B.
- Lundell, D.
- Madison, V.
- Mazzola, R D.
- McKittrick, B.
- Neng-Yang, S.
- Niu, X.
- Orth, P.
- Sinning, L.
- Spitler, J.
- Sun, J.
- Zhou, G.
- Zhu, Z.
- Cleavage on pair of basic residue
- Glycoprotein
- Hydrolase
- Membrane
- Metal-binding
- Metalloprotease
- Notch signaling pathway
- Phosphoprotein
- Protease
- Sh3-binding
- Transmembrane
- Zn-endopeptidase
- Zymogen
