2k9r: Difference between revisions

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==About this Structure==
==About this Structure==
2K9R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9R OCA].  
2K9R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9R OCA].  


==Reference==
==Reference==
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[[Category: Secreted]]
[[Category: Secreted]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 3 09:32:58 2009''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 16:32:05 2009''

Revision as of 13:32, 10 June 2009

File:2k9r.png

Template:STRUCTURE 2k9r

Enhancing the activity of insulin by stereospecific unfolding

Template:ABSTRACT PUBMED 19321436

Disease

Known disease associated with this structure: Hyperproinsulinemia, familial, with or without diabetes OMIM:[176730]

About this Structure

2K9R is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Hua QX, Xu B, Huang K, Hu SQ, Nakagawa S, Jia W, Wang S, Whittaker J, Katsoyannis PG, Weiss MA. Enhancing the activity of a protein by stereospecific unfolding: conformational life cycle of insulin and its evolutionary origins. J Biol Chem. 2009 May 22;284(21):14586-96. Epub 2009 Mar 25. PMID:19321436 doi:10.1074/jbc.M900085200

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