Nitric Oxide Synthase: Difference between revisions
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The oxygenase domain is where the production of NO takes place, whereas the reductase domain provides the electrons necessary to drive the reaction in the oxygenase domain. | The oxygenase domain is where the production of NO takes place, whereas the reductase domain provides the electrons necessary to drive the reaction in the oxygenase domain. | ||
The reaction is: | The reaction is: | ||
[[image:Makroprojekt-chemdraw-1-.gif|frame|center]] | |||
[[image:Makroprojekt-chemdraw-1-.gif]] | |||
The amino acid L-Arginine is turned in to L-Citrulline and NO. The reaction is driven by the oxidation of NADPH to NADP+, which in total yields 5 electrons for the reaction. | The amino acid L-Arginine is turned in to L-Citrulline and NO. The reaction is driven by the oxidation of NADPH to NADP+, which in total yields 5 electrons for the reaction. | ||
The reaction above therefore takes both the oxygenase and the reductase domain into account. | The reaction above therefore takes both the oxygenase and the reductase domain into account. | ||
== The Oxygenase domain of NOS == | == The Oxygenase domain of NOS == | ||
