1r8i: Difference between revisions

Line 1:

[[Image:1r8i.jpg|left|200px]]<br /><applet load="1r8i" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1r8i.jpg|left|200px]]<br /><applet load="1r8i" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1r8i, resolution 3.00Å" />

'''Crystal structure of TraC'''<br />

==Overview==

Type IV secretion systems mediate intercellular transfer of, macro-molecules via a mechanism ancestrally related to that of bacterial, conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the, VirB5 family of proteins, an essential component of most type IV secretion, systems. Here, we present the structure of TraC. VirB5/TraC is a single, domain protein, which consists of a three helix bundle and a loose, globular appendage. Structure-based site-directed mutagenesis followed by, functional studies indicates that VirB5 proteins participate in, protein-protein interactions important for pilus assembly and function.

Type IV secretion systems mediate intercellular transfer of macro-molecules via a mechanism ancestrally related to that of bacterial conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the VirB5 family of proteins, an essential component of most type IV secretion systems. Here, we present the structure of TraC. VirB5/TraC is a single domain protein, which consists of a three helix bundle and a loose globular appendage. Structure-based site-directed mutagenesis followed by functional studies indicates that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.

==About this Structure==

1R8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA].

1R8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA].

==Reference==

Line 14:

[[Category: Single protein]]

[[Category: Baron, C.]]

[[Category: Beck, M.R.]]

[[Category: Beck, M R.]]

[[Category: Waksman, G.]]

[[Category: Yeo, H.J.]]

[[Category: Yeo, H J.]]

[[Category: Yuan, Q.]]

[[Category: helical bundle]]

Line 22:

[[Category: virb5]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Sat Nov 24 22~~:20~~:44 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:48:20 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1r8i.jpg|left|200px]]<br /><applet load="1r8i" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1r8i.jpg|left|200px]]<br /><applet load="1r8i" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1r8i, resolution 3.00&Aring;" />
 '''Crystal structure of TraC'''<br />
 ==Overview==
-Type IV secretion systems mediate intercellular transfer of, macro-molecules via a mechanism ancestrally related to that of bacterial, conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the, VirB5 family of proteins, an essential component of most type IV secretion, systems. Here, we present the structure of TraC. VirB5/TraC is a single, domain protein, which consists of a three helix bundle and a loose, globular appendage. Structure-based site-directed mutagenesis followed by, functional studies indicates that VirB5 proteins participate in, protein-protein interactions important for pilus assembly and function.
+Type IV secretion systems mediate intercellular transfer of macro-molecules via a mechanism ancestrally related to that of bacterial conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the VirB5 family of proteins, an essential component of most type IV secretion systems. Here, we present the structure of TraC. VirB5/TraC is a single domain protein, which consists of a three helix bundle and a loose globular appendage. Structure-based site-directed mutagenesis followed by functional studies indicates that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.
 ==About this Structure==
-R8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA].
+R8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R8I OCA].
 ==Reference==
@@ Line 14: / Line 14: @@
 [[Category: Single protein]]
 [[Category: Baron, C.]]
-[[Category: Beck, M.R.]]
+[[Category: Beck, M R.]]
 [[Category: Waksman, G.]]
-[[Category: Yeo, H.J.]]
+[[Category: Yeo, H J.]]
 [[Category: Yuan, Q.]]
 [[Category: helical bundle]]
@@ Line 22: / Line 22: @@
 [[Category: virb5]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 22:20:44 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:48:20 2008''