3g1r: Difference between revisions

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[[Image:3g1r.jpg|left|200px]]
[[Image:3g1r.png|left|200px]]


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===Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A===
===Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A===


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{{ABSTRACT_PUBMED_19515843}}


==About this Structure==
==About this Structure==
3G1R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1R OCA].  
3G1R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G1R OCA].  
==Reference==
<ref group="xtra">PMID:19515843</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
[[Category: Costanzo, L Di.]]
[[Category: Costanzo, L Di.]]
[[Category: Drury, J.]]
[[Category: Drury, J E.]]
[[Category: Penning, T.]]
[[Category: Penning, T M.]]
[[Category: Bile acid catabolism]]
[[Category: Bile acid catabolism]]
[[Category: Cytoplasm]]
[[Category: Cytoplasm]]
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[[Category: Steroid metabolism]]
[[Category: Steroid metabolism]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 18:03:36 2009''
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Revision as of 06:58, 6 January 2010

File:3g1r.png

Template:STRUCTURE 3g1r

Crystal structure of human liver 5beta-reductase (AKR1D1) in complex with NADP and Finasteride. Resolution 1.70 A

Template:ABSTRACT PUBMED 19515843

About this Structure

3G1R is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Drury JE, Di Costanzo L, Penning TM, Christianson DW. Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex. J Biol Chem. 2009 Jul 24;284(30):19786-90. Epub 2009 Jun 10. PMID:19515843 doi:10.1074/jbc.C109.016931

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